Primary Identifier | MGI:5007248 | Allele Type | Targeted |
Attribute String | Null/knockout, Reporter | Gene | Mia3 |
Transmission | Germline | Strain of Origin | 129S5/SvEvBrd |
Is Recombinase | false | Is Wild Type | false |
Project Collection | Lexicon |
description | See also, data as provided by Lexicon Genetics, Inc. |
molecularNote | A lacZ/neo fusion cassette was inserted in frame 11 bases into the beginning of the second exon, replacing this exon and all of exon3. Western blot analysis confirmed the absence of the large SH3 domain containing isoform and the presence of an about 80-90 kD isoform lacking the SH3 domain in homozygous embryos. |