| Type | MGI:General | Description | in response to UVB radiation, primary keratinocytes from mutant mice show impaired induction of E2F1 protein relative to wild-type controls treatment with doxorubicin, which causes double-strand DNA breakage, increases E2F1 protein levels in mutant MEFs to a lesser extent than in wild-type MEFs following exposure to UVB, mutant MEFs show impaired recruitment of E2F1 and decreased association of GCN5, acetylated H3K9, and NER factors with damaged DNA |
