|  Help  |  About  |  Contact Us

Protein Coding Gene : Tspyl2 TSPY-like 2

Primary Identifier  MGI:106244 Organism  mouse, laboratory
Chromosome  X NCBI Gene Number  52808
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable chromatin binding activity and histone binding activity. Predicted to be involved in negative regulation of DNA replication and negative regulation of cell growth. Predicted to act upstream of or within chromatin organization. Predicted to be located in nucleolus. Predicted to be part of chromatin. Predicted to be active in nucleus. Is expressed in several structures, including alimentary system; genitourinary system; heart; nervous system; and sensory organ. Orthologous to human TSPYL2 (TSPY like 2).
PHENOTYPE: Mice homozygous or hemizygous for a targeted allele are viable, fertile and do not exhibit increased tumor incidence; however, mutant mouse embryonic fibroblasts are impaired in cell cycle arrest following DNA damage induced by ionizing radiation. [provided by MGI curators]
  • synonyms:
  • TSPY-like 2,
  • DNA segment, Chr X, Brigham & Women's Genetics 1396 expressed,
  • DXHXS1008E,
  • MGI:1926887,
  • E130307F10Rik,
  • MGI:1924263,
  • DNA segment, Chr X, 1008 expressed,
  • DNA segment, Chr X, human DXS1008E,
  • MGD-MRK-33936,
  • Tspyl2,
  • RIKEN cDNA E130307F10 gene,
  • DENTT,
  • CINAP,
  • DXBwg1396e

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For