| Primary Identifier | MGI:96782 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 16866 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Predicted to enable hormone activity. Involved in organic cyclic compound metabolic process. Acts upstream of or within luteinizing hormone signaling pathway involved in ovarian follicle development. Located in cytoplasm. Is expressed in alimentary system; brain; genitourinary system; and heart. Human ortholog(s) of this gene implicated in hypogonadotropic hypogonadism 23 with or without anosmia. Orthologous to several human genes including LHB (luteinizing hormone subunit beta). PHENOTYPE: Homozygous null mice display male and female infertility, hypogonadism, azoospermia, absent corpora lutea, degenerating oocytes, and reduced serum levels of estradiol, progesterone, and testosterone. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
