Primary Identifier | MGI:2386711 | Organism | mouse, laboratory |
Chromosome | 6 | NCBI Gene Number | 232223 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Enables thioredoxin-disulfide reductase (NADP) activity. Acts upstream of or within blastocyst formation; cellular oxidant detoxification; and glutathione metabolic process. Predicted to be located in nucleoplasm. Predicted to be active in cytosol and mitochondrion. Is expressed in early conceptus; embryo; secondary oocyte; and telencephalon. Orthologous to human TXNRD3 (thioredoxin reductase 3). PHENOTYPE: Mice exhibit reduced male fertility associated with oligozoospermia and asthenozoospermia. [provided by MGI curators] |