| Primary Identifier | IPR004607 | Type | Family |
| Short Name | GART |
| description | Phosphoribosylglycinamide formyltransferase, also known as GAR transformylase or GART, is an essential enzyme that catalyzes the third step in de novo purine biosynthesis []. This enzyme uses formyl tetrahydrofolate as a formyl group donor to produce 5'-phosphoribosyl-N-formylglycinamide. In prokaryotes, GART is a single domain protein []but in most eukaryotes GART (purN) resides in the C-terminal portion of a large multifunctional protein which also contains GAR synthetase (purD) and aminoimidazole ribonucleotide (AIR) synthetase (purM) activities []. |
