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Allele : Otx2<tm9Asim> orthodenticle homeobox 2; targeted mutation 9, Antonio Simeone

Primary Identifier  MGI:4365828 Allele Type  Targeted
Gene  Otx2 Transmission  Germline
Strain of Origin  129P2/OlaHsd Is Recombinase  false
Is Wild Type  false
molecularNote  The major and two cryptic splice sites upstream from the translation initiation codon were mutagenized and a floxed neo cassette was inserted into the downstream intron. The absence of protein expression of isoforms A and B was confirmed by western blot analysis. Expression of isoforms C and D are normal.
  • mutations:
  • Insertion,
  • Nucleotide substitutions
  • synonyms:
  • Otx2<delta3SS>,
  • Otx2<delta3SS>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

4 Publication categories

Trail: Allele