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Allele : Trpm8<tm1Jul> transient receptor potential cation channel, subfamily M, member 8; targeted mutation 1, David Julius
Primary Identifier  MGI:3716518 Allele Type  Targeted
Attribute String  Null/knockout Gene  Trpm8
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  The self excising ACN cassette was inserted to replace exons 13 and 14. Amino acids 594-661, located in the presumptive cytoplasmic amino-terminal domain, were deleted from the locus, introducing a premature stop codon before and a frame shift after the deleted region. RT-PCR confirmed absence of transcript from mutant trigeminal ganglia.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Trpm8<->,
  • trpm8<-(DJ)>,
  • Trpm8<->,
  • trpm8<-(DJ)>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

37 Publication categories

Trail: Allele




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