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Protein Coding Gene : Gng5 G protein subunit gamma 5

Primary Identifier  MGI:109164 Organism  mouse, laboratory
Chromosome  3 NCBI Gene Number  14707
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable G-protein beta-subunit binding activity and PDZ domain binding activity. Acts upstream of or within positive regulation of neural precursor cell proliferation and positive regulation of secondary heart field cardioblast proliferation. Located in mitochondrion. Is expressed in several structures, including cerebellum; early conceptus; oocyte; and retina. Orthologous to human GNG5 (G protein subunit gamma 5).
PHENOTYPE: Mice homozygous for a null allele exhibit abnormal headfolds, hypoplastic pharyngeal arches, severe cardiac defects including absence of formation of the right ventricle and outflow tract, and complete embryonic lethality. [provided by MGI curators]
  • synonyms:
  • G(y)5,
  • G protein subunit gamma 5,
  • MGD-MRK-38208,
  • Gng5

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

59 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For