Primary Identifier | MGI:3804480 | Allele Type | Targeted |
Attribute String | Null/knockout, Reporter | Gene | Stx1b |
Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Mice carrying the XTB allele were crossed to protamine-cre expressing animals and germ line cre-meditated excised the endogenous exon 7 carrying the GFP insert with the neomycin-selection cassette, leaving the mutated one behind. The resulting allele encodes the 'open' syntaxin-1B protein conformation. |