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Protein Coding Gene : Aven apoptosis, caspase activation inhibitor
Primary Identifier  MGI:1921518 Organism  mouse, laboratory
Chromosome  2 NCBI Gene Number  74268
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Predicted to be involved in negative regulation of G2/M transition of mitotic cell cycle and negative regulation of apoptotic process. Predicted to act upstream of or within apoptotic process. Predicted to be located in membrane. Is expressed in several structures, including heart; liver; metanephros; spleen; and testis. Orthologous to human AVEN (apoptosis and caspase activation inhibitor).
PHENOTYPE: Mice homozygous for a reporter allele exhibit increased cell death in response to various apoptotic stimuli. [provided by MGI curators]
  • synonyms:
  • RIKEN cDNA 1700013A01 gene,
  • mAven-L,
  • mAven-S,
  • Aven,
  • 1700013A01Rik,
  • MGI:1916615,
  • RIKEN cDNA 1700056A21 gene,
  • apoptosis, caspase activation inhibitor,
  • 1700056A21Rik
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Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

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2 Involved In Mutations

Trail: ProteinCodingGene

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0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

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Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

7 Pathways

Trail: ProteinCodingGene

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

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