First Author | Yanagisawa K | Year | 1992 |
Journal | FEBS Lett | Volume | 302 |
Issue | 1 | Pages | 51-3 |
PubMed ID | 1587353 | Mgi Jnum | J:61 |
Mgi Id | MGI:48601 | Doi | 10.1016/0014-5793(92)80282-l |
Citation | Yanagisawa K, et al. (1992) Murine ST2 gene is a member of the primary response gene family induced by growth factors. FEBS Lett 302(1):51-3 |
abstractText | The murine ST2 gene, which encodes a protein remarkably similar to the extracellular portion of murine interleukin 1 receptor types 1 and 2, is expressed in growth-stimulated BALB/c-3T3 cells in the presence of 50 micrograms/ml of cycloheximide. The treatment with 1,000 U/ml of purified native murine beta-interferon superinduced, rather than suppressed, the ST2 mRNA expression as in the cases of c-myc and JE mRNAs. These results suggested that the murine ST2 gene belongs to the family of primary response genes induced by growth factors. Furthermore, a longer ST2-related mRNA was found in BALB/c-3T3 cells that were stimulated to proliferate in the presence of cycloheximide. |