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Publication : Murine ST2 gene is a member of the primary response gene family induced by growth factors.

First Author  Yanagisawa K Year  1992
Journal  FEBS Lett Volume  302
Issue  1 Pages  51-3
PubMed ID  1587353 Mgi Jnum  J:61
Mgi Id  MGI:48601 Doi  10.1016/0014-5793(92)80282-l
Citation  Yanagisawa K, et al. (1992) Murine ST2 gene is a member of the primary response gene family induced by growth factors. FEBS Lett 302(1):51-3
abstractText  The murine ST2 gene, which encodes a protein remarkably similar to the extracellular portion of murine interleukin 1 receptor types 1 and 2, is expressed in growth-stimulated BALB/c-3T3 cells in the presence of 50 micrograms/ml of cycloheximide. The treatment with 1,000 U/ml of purified native murine beta-interferon superinduced, rather than suppressed, the ST2 mRNA expression as in the cases of c-myc and JE mRNAs. These results suggested that the murine ST2 gene belongs to the family of primary response genes induced by growth factors. Furthermore, a longer ST2-related mRNA was found in BALB/c-3T3 cells that were stimulated to proliferate in the presence of cycloheximide.
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