| First Author | Murray HW | Year | 2006 |
| Journal | Infect Immun | Volume | 74 |
| Issue | 7 | Pages | 4370-4 |
| PubMed ID | 16790814 | Mgi Jnum | J:110039 |
| Mgi Id | MGI:3630359 | Doi | 10.1128/IAI.00422-06 |
| Citation | Murray HW, et al. (2006) Responses to Leishmania donovani in mice deficient in interleukin-12 (IL-12), IL-12/IL-23, or IL-18. Infect Immun 74(7):4370-4 |
| abstractText | Interleukin-12 (IL-12) orchestrates acquired resistance in intracellular Leishmania donovani infection in the liver, inducing gamma interferon and, in turn, macrophage activation and parasite killing. Nevertheless, testing in IL-18(-/-) mice compared to wild-type mice and in IL-12p40(-/-) compared to IL-12p35(-/-) mice also suggested both early-acting (IL-18) and late-acting (IL-23) antileishmanial effects independent of IL-12. |
