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Protein Coding Gene : Trmt10a tRNA methyltransferase 10A

Primary Identifier  MGI:1920421 Organism  mouse, laboratory
Chromosome  3 NCBI Gene Number  108943
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable tRNA (guanosine(9)-N1)-methyltransferase activity and tRNA binding activity. Acts upstream of or within magnesium ion homeostasis. Predicted to be located in actin cytoskeleton and nucleolus. Predicted to be active in cytosol and nucleoplasm. Is expressed in Meckel's cartilage; skeleton; and ventral grey horn. Orthologous to human TRMT10A (tRNA methyltransferase 10A).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit increased circulating magnesium level. [provided by MGI curators]
  • synonyms:
  • AA794508,
  • tRNA methyltransferase 10A,
  • Trmt10a,
  • Rg9mtd2,
  • RNA (guanine-9-) methyltransferase domain containing 2,
  • expressed sequence AA794508,
  • MGI:3034323,
  • 3110023L08Rik,
  • RIKEN cDNA 3110023L08 gene

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Genome

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2 Involved In Mutations

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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

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Canonical gene --> Transcripts in specific strains.

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