| First Author | Wineinger MA | Year | 1998 |
| Journal | Muscle Nerve | Volume | 21 |
| Issue | 8 | Pages | 1075-7 |
| PubMed ID | 9655128 | Mgi Jnum | J:116332 |
| Mgi Id | MGI:3694038 | Doi | 10.1002/(sici)1097-4598(199808)21:8<1075::aid-mus14>3.0.co;2-t |
| Citation | Wineinger MA, et al. (1998) The effect of age and temperature on mdx muscle fatigue. Muscle Nerve 21(8):1075-7 |
| abstractText | We have studied the in vitro contractile and fatigue characteristics of extensor digitorum longus (EDL) muscles from 8- and 62-week-old dystrophin-deficient (mdx) and control mice at 20 degrees C and 35 degrees C. There were no differences in fatigability at 20 degrees C, but at 35 degrees C the dystrophin-deficient muscles demonstrated increased fatigability compared to controls, with the older mice exhibiting the greatest fatigue. These results suggest a temperature-related mechanism of myofibrillar fatigue in dystrophin-deficient EDL muscles. |
