| Primary Identifier | MGI:2685844 | Organism | mouse, laboratory |
| Chromosome | 2 | NCBI Gene Number | 381359 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables histone chaperone activity. Involved in negative regulation of transcription by RNA polymerase II. Acts upstream of or within neurogenesis. Predicted to be located in nucleoplasm. Predicted to be active in nucleus. Is expressed in several structures, including future brain and nervous system. Human ortholog(s) of this gene implicated in hereditary sensory and autonomic neuropathy type 8. Orthologous to human PRDM12 (PR/SET domain 12). PHENOTYPE: Mice homozygous for a null allele exhibit neonatal lethality, apoptosis of nociception neurons, and small trigemminal, superior jugular, and dorsal root ganglia. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
