| Primary Identifier | MGI:6140086 | Allele Type | Endonuclease-mediated |
| Attribute String | Null/knockout | Gene | Tafa3 |
| Strain of Origin | C57BL/6NTac | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | A TALEN-mediated mutation was produced by targeting exon 4, which contains the initiation codon ATG. A 43-bp deletion from this genomic region was confirmed by sequencing, resulting in a frameshift mutation with a premature stop codon. RT-PCR analysis confirmed the absence of mRNA expression in whole brain lysates without the hippocampus as well as in hippocampus only lysates from homozygous mutant mice. |
