Primary Identifier | MGI:2668443 | Organism | mouse, laboratory |
Chromosome | 4 | NCBI Gene Number | 242285 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Predicted to enable NAD-retinol dehydrogenase activity; RNA polymerase II-specific DNA-binding transcription factor binding activity; and transcription corepressor activity. Predicted to be involved in keratinocyte proliferation; negative regulation of macromolecule biosynthetic process; and retinoid metabolic process. Predicted to be located in endoplasmic reticulum membrane and nucleus. Predicted to be part of chromatin and transcription repressor complex. Predicted to be active in lipid droplet. Predicted to colocalize with endoplasmic reticulum and plasma membrane. Orthologous to human SDR16C5 (short chain dehydrogenase/reductase family 16C member 5). PHENOTYPE: Mice homozygous for a deletion of Sdr16c5 and Sdr16c6 exhibit accelerated hair growth enlarged meibomian glands. [provided by MGI curators] |