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Allele : Abl1<m1> c-abl oncogene 1, non-receptor tyrosine kinase; mutation 1

Primary Identifier  MGI:1856663 Allele Type  Targeted
Attribute String  Null/knockout Gene  Abl1
Transmission  Germline Strain of Origin  129S/SvEv-Gpi1<c>
Is Recombinase  false Is Wild Type  false
molecularNote  A promoterless neomycin resistance gene was inserted into coding sequences corresponding to the carboxy terminus of the protein, downstream of the tyrosine kinase domain and nuclear targeting sequences. This allele expresses a protein with a functional kinase domain but a disrupted carboxy terminus containing the DNA and actin binding domains.
  • mutations:
  • Insertion
  • synonyms:
  • abl<m1>,
  • abl<m1>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

4 Carried By

Trail: Allele

0 Driven By

12 Publication categories

Trail: Allele