Primary Identifier | MGI:2155337 | Allele Type | QTL |
Gene | Tbs1 | Inheritance Mode | Not Specified |
Strain of Origin | I/StSnEgYCit | Is Recombinase | false |
Is Wild Type | false |
description | This locus affects M. tuberculosis-induced body weight loss in female animals. This allele appears to interact with I/StYCit-derived alleles at D17Mit175 to increase neutrophil inflammation following challenge with M. tuberculosis. |
molecularNote | The heterozygous state confers increased body weight loss and increased survival time in female animals infected with Mycobacterium tuberculosis. |