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Protein Coding Gene : Tcim transcriptional and immune response regulator

Primary Identifier  MGI:1916318 Organism  mouse, laboratory
Chromosome  8 NCBI Gene Number  69068
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable Notch binding activity. Acts upstream of or within regulation of hemopoiesis. Located in cytoplasm and nucleus. Is expressed in lower jaw molar; nasal epithelium; olfactory epithelium; and upper jaw molar. Orthologous to human TCIM (transcriptional and immune response regulator).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit myeloid and lymphoid hyperplasia, an increased number of small-sized red blood cells, increased hematopoietic stem cell number, and enhanced hematopoietic activity. [provided by MGI curators]
  • synonyms:
  • 1110065B09Rik,
  • 1810011O10Rik,
  • AW121743,
  • AW321058,
  • RIKEN cDNA 1110065B09 gene,
  • MGI:2142785,
  • MGI:2142767,
  • expressed sequence AW321058,
  • expressed sequence AW121743,
  • transcriptional and immune response regulator,
  • Tcim,
  • MGI:1915083,
  • RIKEN cDNA 1810011O10 gene

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