Primary Identifier | IPR029811 | Type | Family |
Short Name | ATF4 |
description | ATF4 belongs to the ATF/cAMP-response element-binding protein family. It is a transcriptional activator that binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters [, ]. It plays a crucial role in the adaptation to stresses by regulating the transcription of many genes []. |