Primary Identifier | MGI:97553 | Organism | mouse, laboratory |
Chromosome | 4 | NCBI Gene Number | 110208 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables phosphogluconate dehydrogenase (decarboxylating) activity. Involved in pentose-phosphate shunt, oxidative branch. Acts upstream of or within pentose biosynthetic process. Is active in cytosol. Is expressed in several structures, including adrenal gland; alimentary system; axial musculature; liver; and orbito-sphenoid. Orthologous to human PGD (phosphogluconate dehydrogenase). PHENOTYPE: T-cell specific knock-out results in more robust development of effector functions in stimulated naïve CD8+ T cells. [provided by MGI curators] |