Primary Identifier | MGI:4939654 | Allele Type | Targeted |
Attribute String | Humanized sequence, Inserted expressed sequence | Gene | Hgf |
Transmission | Germline | Strain of Origin | 129S6/SvEvTac |
Is Recombinase | false | Is Wild Type | false |
description | ES cells = JB26A10 (129S6/SvEvTac) |
molecularNote | A targeting vector was designed to replace exons 3-6 of the mouse hepatocyte growth factor (Hgf) locus with a cDNA sequence encoding exons 2-18 of the human hepatocyte growth factor (HGF), a polyA signal, and a frt-flanked PGK-neo cassette. Flp-mediated recombination removed the neo cassette. |