Primary Identifier | MGI:2388375 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Rdh5 |
Transmission | Germline | Strain of Origin | 129/Sv |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The gene was disrupted by replacement of exons 1-3 with a neomycin resistance cassette via homologous recombination. Absence of gene expression in homozygous mutant animals was verified by RT-PCR analysis of total RNA from eyes and kidneys, and by Western blot analysis of eye protein extracts. |