| Primary Identifier | MGI:1352448 | Organism | mouse, laboratory |
| Chromosome | 19 | NCBI Gene Number | 329064 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Enables several functions, including calcium ion binding activity; identical protein binding activity; and transmembrane transporter binding activity. Contributes to monoatomic cation transmembrane transporter activity and sour taste receptor activity. Involved in several processes, including cellular response to acidic pH; detection of chemical stimulus involved in sensory perception of sour taste; and protein tetramerization. Acts upstream of or within monoatomic cation transmembrane transport. Located in endoplasmic reticulum and plasma membrane. Part of calcium channel complex and receptor complex. Colocalizes with cell surface. Is expressed in cochlea; medulla oblongata; spinal cord; and tongue. Orthologous to human PKD2L1 (polycystin 2 like 1, transient receptor potential cation channel). PHENOTYPE: Mice homozygous for a knock-out allele exhibit decreased chorda tympani nerve response to sour tastants. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
