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Protein Coding Gene : Aak1 AP2 associated kinase 1
Primary Identifier  MGI:1098687 Organism  mouse, laboratory
Chromosome  6 NCBI Gene Number  269774
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Predicted to enable AP-2 adaptor complex binding activity; Notch binding activity; and protein serine/threonine kinase activity. Involved in presynaptic endocytosis. Located in presynapse. Is expressed in cranial ganglion; dorsal root ganglion; retina nuclear layer; and telencephalon. Orthologous to human AAK1 (AP2 associated kinase 1).
  • synonyms:
  • R75501,
  • BC028270,
  • AU067726,
  • Aak1,
  • AP2 associated kinase 1,
  • AU067724,
  • mKIAA1048,
  • expressed sequence C79663,
  • RIKEN cDNA 5530400K14 gene,
  • MGI:2141755,
  • expressed sequence AU067726,
  • 5530400K14Rik,
  • MGI:2141601,
  • expressed sequence AU067724,
  • MGI:2679265,
  • C79663,
  • MGC:40785,
  • DNA segment, Chr 6, ERATO Doi 245, expressed,
  • MGI:2141797,
  • cDNA sequence BC028270,
  • MGI:2141600,
  • MGI:1925924,
  • expressed sequence R75501,
  • D6Ertd245e
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Features --> Cross References

Genome

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1 Involved In Mutations

Trail: ProteinCodingGene

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0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

4 Pathways

Trail: ProteinCodingGene

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

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