|  Help  |  About  |  Contact Us

Allele : Tg(Pbsn-PKN1*)#Bmp transgene insertion, Bryce M Paschal

Primary Identifier  MGI:6159652 Allele Type  Transgenic
Attribute String  Constitutively active, Humanized sequence, Inserted expressed sequence Gene  Tg(Pbsn-PKN1*)#Bmp
Strain of Origin  Not Specified Is Recombinase  false
Is Wild Type  false
molecularNote  The -244 to -96 region of Pbsn promoter linked to androgen receptor binding sites 1 and 2 drives expression of a human PKN1 cDNA transcript variant 2 (NM_002741) with mutations of K644E, T774E, S916A, and N-terminal deletion of 1-568 amino acids. The protein expressed by this transgene is constitutively active.
  • mutations:
  • Insertion
  • synonyms:
  • PbPKN1deltaN,
  • PbPKN1deltaN
Quick Links:
 
Quick Links:
 

1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

2 Publication categories

Trail: Allele