| Primary Identifier | IPR030367 | Type | Family |
| Short Name | ABCA5 |
| description | ATP-binding cassette subfamily A member 5 (ABCA5) belongs to the ABC transporter family, whose remembers are full-length transporters organised in two tandem halves, each with a hydrophobic TMD followed by a cytoplasmic NBD [].In mice, ABCA5 localises to lysosomes and late endosomes. It is linked to lysosomal disease []. In humans, it may have a role in tumour development []. ABCA5 in the brain seems to function as a cholesterol transporter associated with amyloid-beta peptides generation []. |
