| Type | MGI:General | Description | mutant mice at 16 weeks of age, starved for 16 hours and then treated with oral administration of glucose, exhibit significantly lower blood glucose levels than control mice, and the glucose disposal is faster than in controls after 8 weeks on a high fat diet, 16 week old mutant mice exhibit hyperglycemia at a level similar to controls and compared to normal diet- fed mice; however, in a fasting condition, mutant mice that had been fed a high fat diet for 8 weeks exhibit a lower blood glucose level than control mice that had been fed a high fat diet for 8 weeks after 8 weeks on a high fat diet, 16 week old mutant mice exhibit lower glucose levels in a glucose tolerance test at 60 and 120 minutes after oral glucose administration than identically -treated controls |
