Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of prostaglandin.
synonyms:
inhibition of prostaglandin biosynthetic process,
down-regulation of prostaglandin biosynthetic process,
downregulation of prostaglandin biosynthetic process,
negative regulation of prostaglandin biosynthesis,
down regulation of prostaglandin biosynthetic process,