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Allele : Ckm<tm1Bew> creatine kinase, muscle; targeted mutation 1, Be Wieringa

Primary Identifier  MGI:2179990 Allele Type  Targeted
Attribute String  Null/knockout Gene  Ckm
Transmission  Germline Strain of Origin  129S7/SvEvBrd-Hprt1<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A 0.9 kb region encompassing exon 2 and part of introns 1 and 2 was replaced with a hygroB resistance cassette via homologous recombination. Northern blot using an exon 2 probe demonstrated lack of gene transcripts in skeletal muscle and staining for enzyme activity was negative in homogenates of skeletal and cardiac muscle from homozygous mutant animals.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • MM-CK-,
  • MMKO,
  • M-CK-,
  • M-CK-,
  • MMKO,
  • MM-CK-
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

37 Publication categories

Trail: Allele