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Protein Coding Gene : Msi2 musashi RNA-binding protein 2
Primary Identifier  MGI:1923876 Organism  mouse, laboratory
Chromosome  11 NCBI Gene Number  76626
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables poly(U) RNA binding activity. Involved in stem cell development. Located in cytoplasm. Is expressed in several structures, including alimentary system; central nervous system; hair follicle; limb bud; and sensory organ. Orthologous to human MSI2 (musashi RNA binding protein 2).
PHENOTYPE: Mice homozygous for a gene trapped allele exhibit lethality, decreased body size, and decreased hematopoietic stem cells. Mice homozygous for a conditional knock-out allele exhibit impaired hematopoietic stem cell physiology upon induction. [provided by MGI curators]
  • synonyms:
  • AI451722,
  • Msi2,
  • musashi RNA-binding protein 2,
  • RIKEN cDNA 1700105C15 gene,
  • MGI:2144175,
  • MGI:2144227,
  • expressed sequence AI563628,
  • AI563628,
  • Musashi2,
  • AW489193,
  • MGI:2144536,
  • msi2h,
  • expressed sequence AW489193,
  • 1700105C15Rik,
  • expressed sequence AI451722
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Features --> Cross References

Genome

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0 Exons

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4 Involved In Mutations

Trail: ProteinCodingGene

0 Strain

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0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

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Function

Mouse features --> Functions (GO terms)

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Genes --> Homologs

Interactions

6 Pathways

Trail: ProteinCodingGene

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

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1 Driver For

Trail: ProteinCodingGene




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