| Primary Identifier | MGI:106016 | Organism | mouse, laboratory |
| Chromosome | 16 | NCBI Gene Number | 20462 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable RNA binding activity; identical protein binding activity; and protein domain specific binding activity. Involved in regulation of RNA splicing. Acts upstream of or within cerebral cortex regionalization; embryonic brain development; and positive regulation of mRNA splicing, via spliceosome. Located in nuclear inner membrane. Is expressed in several structures, including brain; central nervous system ganglion; extraembryonic component; olfactory epithelium; and retina. Orthologous to human TRA2B (transformer 2 beta homolog). PHENOTYPE: Mice homozygous for a knock-out allele exhibit reduced embryo size and early embryonic lethality associated with deficient vasculogenesis and abnormal allantois morphology. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
