| Type | MGI:General | Description | altered lung-bud orientation and reduced branching morphogenesis is noted at E10.5-E11; a caudal and lateral shift in the orientation of the accessory lobe, and a lateral shift in the middle and cranial lobe positions are commonly observed a range of fusion defects in the right pulmonary lobes are noted at E12-E13 by E18, most embryonic lungs display fusion of the accessory and caudal lobes and abnormal orientation of the accessory lobe at E18, ~13% of embryonic lungs exhibit more severe malformations in which the cranial, caudal, and middle lobes are fused |
