First Author | Lesage F | Year | 1992 |
Journal | FEBS Lett | Volume | 310 |
Issue | 2 | Pages | 162-6 |
PubMed ID | 1383027 | Mgi Jnum | J:2710 |
Mgi Id | MGI:51232 | Doi | 10.1016/0014-5793(92)81320-l |
Citation | Lesage F, et al. (1992) Developmental expression of voltage-sensitive K+ channels in mouse skeletal muscle and C2C12 cells. FEBS Lett 310(2):162-6 |
abstractText | The developmental expression of voltage-sensitive K+ channels was analyzed by Northern blot in mouse skeletal muscle. Of nine Shaker-like genes studied, eight are expressed in this mammalian muscle. Their expression is differentially regulated during development. The mouse cell line C2C12 has been used to study expression of voltage-sensitive K+ channels during in vitro myotube differentiation. Different voltage-sensitive K+ channel messages are also expressed in these cells which display a pattern of expression depending upon the differentiation stage. The message for the very peculiar K+ channel of IsK type could only be detected by polymerase chain reaction on skeletal muscle mRNA. |