Primary Identifier | IPR032354 | Type | Domain |
Short Name | FOXP-CC |
description | This coiled-coil domain, approximately 60-70 residues in length, is mainly found in Forkhead box proteins from animals []. It modulates the dimeric associations of FOXP transcription factors. Several mutations found in this domain have been linked to the IPEX syndrome (immunodysregulation polyendocrinopathy enteropathy X-linked syndrome) []. |