Primary Identifier | IPR031286 | Type | Family |
Short Name | AMIGO2 |
description | The Amphoterin-induced protein (AMIGO) family consists of three cell surface leucine-rich repeat (LRR) proteins: AMIGO -1, -2, -3. AMIGO-1 is predominantly expressed in the nervous system, whereas the other two members of the family are expressed more broadly []. AMIGO-2 promotes depolarisation-dependent survival of the granule neuron []. It has a potential role in gastric adenocarcinoma []. |