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Allele : Sox2<tm1Rlb> SRY (sex determining region Y)-box 2; targeted mutation 1, Robin Lovell-Badge

Primary Identifier  MGI:2449045 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Sox2
Transmission  Germline Strain of Origin  129S/SvEv-Gpi1<c>
Is Recombinase  false Is Wild Type  false
description  Phenotypic Similarity to Human Syndrome: Pituitary Hormone Deficiency, Combined (J:114458)
molecularNote  The coding region of the gene was replaced with a beta-geo cassette via homologous recombination. LacZ staining in heterozygous embyros showed an expression pattern similar to that of endogenous Sox2.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Sox2<betageo>,
  • Sox2<betageo>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

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0 Driven By

15 Publication categories

Trail: Allele