Primary Identifier | MGI:2449045 | Allele Type | Targeted |
Attribute String | Null/knockout, Reporter | Gene | Sox2 |
Transmission | Germline | Strain of Origin | 129S/SvEv-Gpi1<c> |
Is Recombinase | false | Is Wild Type | false |
description | Phenotypic Similarity to Human Syndrome: Pituitary Hormone Deficiency, Combined (J:114458) |
molecularNote | The coding region of the gene was replaced with a beta-geo cassette via homologous recombination. LacZ staining in heterozygous embyros showed an expression pattern similar to that of endogenous Sox2. |