Primary Identifier | MGI:5553464 | Allele Type | Transgenic |
Attribute String | Humanized sequence, Inserted expressed sequence | Gene | Tg(Prnp-APPSweArc)#Rmni |
Strain of Origin | (C57BL/6 x DBA/2)F1 | Is Recombinase | false |
Is Wild Type | false |
molecularNote | The human APP695 containing the Swedish K670N and M671L and Artic E693G mutations is under the control of the prion protein promoter. The pound symbol (#) is used because the line is not specified, although the line used has a 6-fold overexpression of APP compared to endogenous APP levels. |