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Publication : Cloning, tissue-specific expression, gene structure and chromosomal localization of human phosphatidylcholine transfer protein.

First Author  Cohen DE Year  1999
Journal  Biochim Biophys Acta Volume  1447
Issue  2-3 Pages  265-70
PubMed ID  10542325 Mgi Jnum  J:58267
Mgi Id  MGI:1347152 Doi  10.1016/s0167-4781(99)00163-3
Citation  Cohen DE, et al. (1999) Cloning, tissue-specific expression, gene structure and chromosomal localization of human phosphatidylcholine transfer protein. Biochim Biophys Acta 1447(2-3):265-70
abstractText  Phosphatidylcholine transfer protein (PC-TP) is a cytosolic protein that catalyzes intermembrane transfer of phosphatidylcholines in vitro. We have cloned a cDNA encoding the human ortholog of PC-TP and have determined its tissue-specific expression as well as genomic organization. Radiation hybrid mapping localized the human gene, PCTP, to chromosome 17q21-22 and PCR-based single strand conformation polymorphism analysis of an interspecific backcross assigned mouse Pctp to the region of syntenic conservation on chromosome 11.
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