| First Author | Eva C | Year | 1992 |
| Journal | FEBS Lett | Volume | 314 |
| Issue | 3 | Pages | 285-8 |
| PubMed ID | 1468559 | Mgi Jnum | J:3466 |
| Mgi Id | MGI:51979 | Doi | 10.1016/0014-5793(92)81490-d |
| Citation | Eva C, et al. (1992) The murine NPY-1 receptor gene. Structure and delineation of tissue-specific expression. FEBS Lett 314(3):285-8 |
| abstractText | The murine gene for the NPY-1 receptor subtype for neuropeptide Y was characterized by DNA sequencing and expression studies. It comprises three exons with a 6,400 bp 5'-untranslated and a 80 bp internal intronic sequence. The 5'-flanking region of this gene lacks TATA or CCAAT consensus sequences in the proximity to the multiple transcription initiation sites. A 1,300 bp genomic fragment of the 5'-flanking region drives the expression of the lacZ reporter gene in NG108-15 cells and primary cultured neurons but not in glial and human embryonic kidney cells. In addition, it contains consensus sequences for various transcription factors including cAMP- and glucocorticoid-responsive elements. |
