First Author | Hata M | Year | 2000 |
Journal | Biochim Biophys Acta | Volume | 1493 |
Issue | 1-2 | Pages | 208-10 |
PubMed ID | 10978524 | Mgi Jnum | J:64474 |
Mgi Id | MGI:1889394 | Doi | 10.1016/s0167-4781(00)00136-6 |
Citation | Hata M, et al. (2000) Murine cDNA encoding a novel type I HSP40/DNAJ homolog, mmDjA4(1). Biochim Biophys Acta 1493(1-2):208-10 |
abstractText | We have cloned a cDNA encoding a novel type I HSP40/DNAJ protein from the mouse EST database, and designated it mmDjA4 (Mus musculus type I DnaJ homolog 4). This cDNA encodes 397 amino acid residues whose sequence shows 67 and 51% identity with the previously identified murine Hsj2 and mDj3, respectively. The sequence of mmDjA4 contains the four repeats of CxxCxGxG motif which are characteristic of type I HSP40/DNAJ proteins, and a CaaX prenylation motif at the carboxy terminus. Northern blot analysis showed that mmDjA4 is specifically expressed in mouse testis and heart. This is the fourth member of the mammalian type I HSP40/DNAJ family to be identified. |