First Author | Augert A | Year | 2014 |
Journal | Cancer Cell | Volume | 26 |
Issue | 6 | Pages | 783-784 |
PubMed ID | 25490443 | Mgi Jnum | J:217686 |
Mgi Id | MGI:5615322 | Doi | 10.1016/j.ccell.2014.11.012 |
Citation | Augert A, et al. (2014) Treating transcriptional addiction in small cell lung cancer. Cancer Cell 26(6):783-4 |
abstractText | Small cell lung cancer (SCLC) is a devastating tumor type with great therapeutic need. In this issue of Cancer Cell, Christensen and colleagues identify THZ1, a CDK7 inhibitor, as a potential therapy for SCLC. Using cells and mouse models, the authors show exquisite sensitivity of SCLC to transcriptional inhibition. |