Primary Identifier | MGI:3712225 | Allele Type | Targeted |
Gene | Igh | Transmission | Germline |
Strain of Origin | 129P2/OlaHsd | Is Recombinase | false |
Is Wild Type | false |
molecularNote | The following point mutations were inserted into the VHB1-8 region: GCT to GGT (Ala24Gly), AGC to ACC (Ser31Thr), CAC to CAG (His35Gln), AGA to ACT (Arg98Thr). A floxed neo included in the vector was subsequently removed via cre mediated recombination. |