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Protein Coding Gene : Myrip myosin VIIA and Rab interacting protein

Primary Identifier  MGI:2384407 Organism  mouse, laboratory
Chromosome  9 NCBI Gene Number  245049
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Enables cytoskeletal protein binding activity; protein kinase A binding activity; and small GTPase binding activity. Predicted to be involved in positive regulation of insulin secretion. Predicted to act upstream of or within vesicle transport along actin filament. Located in several cellular components, including actin cytoskeleton; melanosome; and photoreceptor outer segment. Part of exocyst. Is expressed in several structures, including gut; heart; lung; male reproductive gland or organ; and nervous system. Orthologous to human MYRIP (myosin VIIA and Rab interacting protein).
PHENOTYPE: Mice homozygous for a null allele exhibit glucose intolerance, decreased insulin secretion, and abnormal insulin granule localization in beta-cells. [provided by MGI curators]
  • synonyms:
  • RIKEN cDNA A230081N12 gene,
  • Myrip,
  • A230081N12Rik,
  • Slac2-c,
  • myosin VIIA and Rab interacting protein,
  • MGI:2444163

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Genome

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Canonical gene --> CDSs in specific strains.

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Canonical gene --> Transcripts in specific strains.

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Proteins

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