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Protein Coding Gene : Cuzd1 CUB and zona pellucida-like domains 1

Primary Identifier  MGI:1202881 Organism  mouse, laboratory
Chromosome  7 NCBI Gene Number  16433
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Involved in trypsinogen activation. Located in zymogen granule membrane. Orthologous to human CUZD1 (CUB and zona pellucida like domains 1).
PHENOTYPE: Female mice homozygous for disruption of this gene exhibit impaired mammary gland development during puberty and during and following pregnancy and do not lactate. Homozygous mutant mice show an increased susceptibility to induced pancreatitis. [provided by MGI curators]
  • synonyms:
  • ERG-1,
  • Itmap1,
  • UO-44,
  • UTCZP,
  • CUB and zona pellucida-like domains 1,
  • integral membrane-associated protein 1,
  • Cuzd1

Features --> Cross References

Genome

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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

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Expression

Gene --> Expression annotations

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Disease

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Literature

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