| Primary Identifier | MGI:4410453 | Allele Type | Transgenic |
| Attribute String | Inducible, Recombinase | Gene | Tg(Ins1-cre/ERT)1Lphi |
| Strain of Origin | CD-1 | Induced With | tamoxifen |
| Is Recombinase | true | Is Wild Type | false |
| molecularNote | An 8.3 kb fragment of the mouse insulin promoter (Ins1; from nucleotide -8280 to +12 relative to the transcriptional start site) drives cDNA encoding cre recombinase fused to the mutated mouse estrogen receptor ligand-binding domain. A 2.1 kb fragment of the hGH gene was added to function as a transcriptional stop signal. The 12.5 kb construct was purified and microinjected into fertilized pronuclei of CD1 mice. Line 1 was established. |
