Primary Identifier | IPR028717 | Type | Family |
Short Name | VAMP2 |
description | Vesicle-associated membrane protein 2 (VAMP2, also known as Synaptobrevin-2) belongs to the VAMP family, which is a group of small, integral membrane proteins of synaptic vesicles that is mostly involved in vesicle fusion. Neurotransmitter release involves the assembly of a heterotrimeric SNARE complex composed of SNAP25, VAMP2 and syntaxin 1 []. VAMP2 plays a specific role in the insulin-dependent recruitment of GLUT4 from its intracellular storage compartment to the cell surface []. |