|  Help  |  About  |  Contact Us

Comment :

Type  MGI:General Description  mice exhibit altered organization of mossy fiber-granule cell synapses within the cerebellar glomeruli at 5 weeks of age, expression analysis of presynaptic markers showed that the number of vGluT2-immunopositive puncta in excitatory mossy fibers is increased, whereas the number of GAD65/67-immunopositive puncta in inhibitory Golgi cell axons is normal relative to wild-type controls at 8 weeks of age, EM revealed an increased number of postsynaptic densities in cerebellar granule cells per mossy fiber terminal relative to wild-type controls